What is Peyronie’s disease?
Peyronie’s disease (PD) is a connective tissue disorder that causes hard scar tissue (plaque buildup) to grow in the penis. Though not visible, this plaque can result in decreased elasticity within the penis at a curvature of 30 degrees or greater.
What causes Peyronie’s disease?
Researchers are still unclear as to what exactly causes PD, but many believe that it can develop after there is trauma that causes bleeding inside the penis, or is genetically linked or inherited. A number of medications list Peyronie’s disease as a side effect, but the chances of developing PD from these medications is so low that there is no substantial evidence to support these claims.
Symptoms of Peyronie’s disease
Like other diseases, symptoms of Peyronie’s disease may develop over time, or may appear overnight. The most common signs and symptoms include:
- Scar tissue: Scar tissue that develops as a result of Peyronie’s disease can easily be felt on the penis. It will feel like a flat lump or a long band of hard tissue.
- A curve to the penis: A significant curve to the penis, whether it upward or downward, is an indication of PD. Sometimes when the penis is erect, you may also notice an “hourglass” appearance, where there is a tight, narrow band around the shaft.
- Erection problems: If you begin experiencing erectile dysfunction, it may be a result of PD.
- Shortening of the penis: Your penis may lose some of its length due to PD.
- Pain: You may experience painful erections or pain when your penis is touched.
When should I see a doctor?
You should make an appointment with your doctor if you begin experiencing any of the signs listed above. Your doctor will be able to provide a proper diagnosis, or rule out other causes of your symptoms, as well as determine a treatment plan.
How is the treatment of Xiaflex administered?
“[Nearly] 250,000 men in the United States have some degree of [PD].Until recently, we had [many] different medications that we would try, all off label and with varying degrees of response but the way to really fix it was surgery,” stated Dr. Evan Goldfischer in an interview with 101.5 WPDH Radio. Xiaflex (collagenase clostridium histolyticum) is an FDA approved prescription medicine that is administered by a trained professional only. Xiaflex is injected directly into the hardened tissue in two courses, and the area is massaged to successfully break down the scar tissue. It is the first non-surgical treatment that can be administered in the doctor’s office. “Finally we have an FDA approved medication that for many patients will avoid the need for major surgery and we’re hoping that patients now will come in earlier,” concluded Dr. Goldfischer.
What are the side effects of Xiaflex?
Xiaflex does have side effects, some which may be serious. Side effects include pain, swelling, or blisters at the injection site, tenderness, painful erections, changes in the color of the skin on your penis, or pain during intercourse. Allergic reactions include hives, swollen face, or chest pains. If you experience any of the side effects listed, contact your physician right away. Visit the manufacturer’s website for a complete list of side effects.
Does my insurance cover Xiaflex treatments?
Xiaflex is currently covered by a number of insurance companies to treat Dupuytren’s contracture, a hand deformity in which the fingers bend toward the palm and cannot be fully extended. Xiaflex has only recently been approved by the FDA for the treatment of PD, and while some insurance companies may not yet cover it, it is expected to be covered by most major insurance companies in the near future. If a patient does not have insurance, financial assistance will be available to eligible patients contingent upon program criteria requirements.
Where can I be treated?
The Physicians of the Urology Division of Premier Medical Group are the first in the area to offer Xiaflex treatment. For more information, call 845-437-5000 to schedule a consultation with one of our physicians.